4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER

4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER - Names and Identifiers

Name	4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER
Synonyms	4-(N-BOC-AMINOMETHYL)PHENYLBORONIC ACID PICOL ESTER 4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER 4-(TERT-BUTOXYCARBONYLAMINOMETHYL)PHENYLBORONIC ACID, PINACOL ESTER tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylcarbamate [4-[[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]methyl]phenyl]boronic acid tert-Butyl [[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]carbamate Tert-butyl N-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]carbamate
CAS	330794-35-9
InChIKey	CUDCEJRRWNIPDL-UHFFFAOYSA-N

4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER - Physico-chemical Properties

Molecular Formula	C18H28BNO4
Molar Mass	333.23
Density	1.06±0.1 g/cm3(Predicted)
Boling Point	452.0±38.0 °C(Predicted)
pKa	12.16±0.46(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
WGK Germany	3

4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER - Upstream Downstream Industry

Downstream Products

4-AMINOMETHYLPHENYLBORONIC ACID, PINACOL ESTER, HCL

4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER - Introduction

4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER is an organic compound with the molecular formula C15H23BNO4. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: A colorless or light yellow solid.
2. Solubility: Soluble in many common organic solvents, such as chloroform, dimethylformamide and dichloromethane.
3. Melting Point: about 78-80 degrees Celsius.

Use:
This compound is commonly used in organic synthesis reactions, especially in metal-catalyzed palladium-catalyzed reactions. It can be used as a protecting group for Phenylboronic acid and has a wide range of applications in the synthesis of drugs and natural products. It can also be used to construct carbon-nitrogen bonds of aromatic compounds.

Method:
Generally, 4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER is prepared by reacting 4-((N-BOC-amino) METHYL)PHENYLBORONIC ACID with PINACOL under alkaline conditions.

Safety Information:
This compound is relatively stable under normal operating conditions, but it still needs to be handled with caution. When handling it, wear appropriate protective gloves and eye protection to avoid contact with skin and inhalation. Care should also be taken to avoid contact with strong oxidants or strong acids to prevent dangerous reactions. When handling or disposing of waste, refer to your local safety practices.

Last Update：2024-04-09 02:00:51